1, 3, 3-Triazolc analogs of the itnidazole intermediates of de novo puriue synthesis have beer1 prepared its potential incdifierr of nucleic acid metabolism. The l-benzyl-1, 2, 3- triazoles mere formed readily by condensing benzyl azide with esters anti nitriles containing an active methylene group and the benzyl group WLS removed by reduction with sodium in liquid ammonia.
