Tetrahedron Letters

A simple one-pot method for the mercuric oxide mediated synthesis of piperazines via oxidative diamination of olefins

H Kour, S Paul, PP Singh, M Gupta, R Gupta

Index: Kour, Harpreet; Paul, Satya; Singh, Parvinder Pal; Gupta, Monika; Gupta, Rajive Tetrahedron Letters, 2013 , vol. 54, # 8 p. 761 - 764

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Citation Number: 5

Abstract

Mercuric oxide mediated one-pot synthesis of substituted piperazines via oxidative diamination of olefins with N-protected ethylene diamine has been reported. Among the various conditions tried, mercuric (II) oxide/tetrafluoroboric acid gave good to excellent yields of the desired products. A series of piperazines have been synthesized and characterized by NMR and mass spectroscopy methods.