Suzuki− Miyaura Coupling of Aryl Carbamates, Carbonates, and Sulfamates

KW Quasdorf, M Riener, KV Petrova…

Index: Quasdorf, Kyle W.; Riener, Michelle; Petrova, Krastina V.; Garg, Neil K. Journal of the American Chemical Society, 2009 , vol. 131, # 49 p. 17748 - 17749

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Citation Number: 190

Abstract

The first Suzuki− Miyaura cross-couplings of carbamates, carbonates, and sulfamates is described. The method provides a powerful means of using simple derivatives of phenol as precursors to polysubstituted aromatic compounds, as exemplified by a concise synthesis of the anti-inflammatory drug flurbiprofen.