An efficient synthesis of new thiazolopyrimidinones under microwave irradiation

…, A Gellis, P Vanelle, H El??Kashef

Index: Djekou, Serge; Gellis, Armand; El-Kashef, Hussein; Vanelle, Patrice Journal of Heterocyclic Chemistry, 2006 , vol. 43, # 5 p. 1225 - 1229

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Citation Number: 5

Abstract

Fused pyrimidines represent an important class of heterocyclic compounds of chemotherapeutic importance. Their antifungal [1], antibacterial [2-5], antiviral [6] and cytotoxic [7] properties are well documented. Thiazolopyrimidines, in particular, are reported to possess various therapeutic properties such as analgesic [8], antiinflammatory [9-12], anti- anxiety [13, 14], antipsychotic [15-18], anti-HIV-1 [19], antidepressant [20], antibacterial [21 ...