Tetrahedron letters

Synthesis and biological evaluation of unnatural canthine alkaloids

…, RG Robinson, SF Barnett, D Defeo-Jones, CW Ross…

Index: Lindsley, Craig W.; Bogusky, Michael J.; Leister, William H.; McClain, Ray T.; Robinson, Ronald G.; Barnett, Stanley F.; Defeo-Jones, Deborah; Ross III, Charles W.; Hartman, George D. Tetrahedron Letters, 2005 , vol. 46, # 16 p. 2779 - 2782

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Citation Number: 35

Abstract

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Employing a 'one-pot' microwave-assisted protocol, unnatural canthine alkaloids with biological activities beyond the natural products have been prepared. This report describes unnatural canthine alkaloid analogs as selective, allosteric Akt kinase inhibitors. ... Galanthamine and the unnatural ...