Organic letters

Synthesis of Multisubstituted Pyridines

Z He, D Dobrovolsky, P Trinchera, AK Yudin

Index: Rotstein, Benjamin H.; Yudin, Andrei K. Synthesis (Germany), 2012 , vol. 44, # 18 p. 2851 - 2858

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Citation Number: 22

Abstract

By utilizing amino allenes, aldehydes, and aryl iodides as readily available building blocks, a simple and modular synthesis of multisubstituted pyridines with flexible control over the substitution pattern has been achieved. The method employs a two-step procedure involving