A general and versatile approach to thermally generated N??heterocyclic carbenes

GW Nyce, S Csihony, RM Waymouth…

Index: Nyce, Gregory W.; Csihony, Szilard; Waymouth, Robert M.; Hedrick, James L. Chemistry - A European Journal, 2004 , vol. 10, # 16 p. 4073 - 4079

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Citation Number: 203

Abstract

Abstract The synthesis of N-heterocyclic carbene (NHC) adducts by condensation of diamines with appropriately substituted benzaldehydes is described. This simplified approach provides the NHC adduct without first having to generate the carbene followed by its protection. These adducts undergo thermal deprotection to generate N-heterocyclic carbene in situ. Adduct decomposition temperatures were investigated as a function of ...