Takanori Fujimura, Takashi Fujimoto, Ryota Hara, Naoki Shimmyo, Yasunori Kobata, Akira Kido, Yasuhiro Akai, Yasuhito Tanaka
Index: Mod. Rheumatol. 25 , 871-5, (2015)
Full Text: HTML
To evaluate the subclinical articular involvement in patients with primary Sjögren's syndrome (pSS) using musculoskeletal ultrasound (MSUS), and to correlate the findings with laboratory results and clinical manifestations.Forty-eight consecutive patients with pSS were enrolled. The bilateral metacarpophalangeal, proximal interphalangeal, and interphalangeal joints were examined using MSUS, and the synovial hypertrophy and power Doppler signal were recorded for each joint using semi-quantitative scores (0 = normal, 1 = mild change compared with undamaged joint, 2 = moderate change, and 3 = severe change).Mild or moderate synovial hypertrophy was found in 151 (15.7%) and 2 (0.2%) out of 960 hand joints, respectively, and power Doppler signals were present in 19 (2.0%) of the 960 joints. While anti-centromere antibody (ACA) was found in 10 patients (20.8%), none of the patients with MSUS-confirmed synovitis was positive for ACA. No other autoantibodies, laboratory tests, or clinical manifestations correlated with MSUS-confirmed synovitis.MSUS is useful for detecting subclinical synovitis in pSS patients. MSUS showed that ACA-positive pSS patients had a low prevalence of synovitis.
Structure | Name/CAS No. | Molecular Formula | Articles |
---|---|---|---|
![]() |
Poly(9,9-dioctylfluorene-co-N-(4-butylphenyl)diphenylamine)
CAS:220797-16-0 |
C51H63N |
Interaction of new kinase inhibitors cabozantinib and tofaci...
2016-04-15 [Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 159 , 199-208, (2016)] |
Mutual effects of melatonin and activin on induction of aldo...
2015-08-01 [J. Steroid Biochem. Mol. Biol. 152 , 8-15, (2015)] |
Porous Organic Cages for Sulfur Hexafluoride Separation.
2016-02-10 [J. Am. Chem. Soc. 138 , 1653-9, (2016)] |
Sitagliptin reduces cardiac apoptosis, hypertrophy and fibro...
2013-01-01 [PLoS ONE 8 , e78330, (2013)] |
Interferon-mediated antiviral activities of Angelica tenuiss...
2016-01-01 [J. Microbiol. 54 , 57-70, (2016)] |
Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer
Copyright © 2024 ChemSrc All Rights Reserved