Catalytic Asymmetric Intramolecular Hydroarylations of ω??Aryloxy??and Arylamino??Tethered α, β??Unsaturated Aldehydes

HH Lu, H Liu, W Wu, XF Wang, LQ Lu…

Index: Lu, Hai-Hua; Liu, Hui; Wu, Wei; Wang, Xu-Fan; Lu, Liang-Qiu; Xiao, Wen-Jing Chemistry - A European Journal, 2009 , vol. 15, # 12 p. 2742 - 2746

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Citation Number: 47

Abstract

Abstract Economical approach: The first organocatalytic asymmetric intramolecular hydroarylation of phenol-and aniline-derived enals offers one of the most straightforward and atom-economic approaches to enantioriched chromans and tetrahydroquinolines (up to 96% ee; see scheme).