e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
2-Amino-5-trifluoromethyl-1, 3, 4-thiadiazole and a redetermination of 2-amino-1, 3, 4-thiadiazole, both at 120 K: chains of edge-fused R22 (8) and R44 (10) …
Molecules of 2-amino-5-trifluoromethyl-1, 3, 4-thiadiazole, C3H2F3N3S, are linked by two independent N—H⋯ N hydrogen bonds into sheets of alternating R22 (8) and R66 (20) rings, while the molecules of the unsubstituted 2-amino-1, 3, 4-thiadiazole, C2H3N3S, are linked, again by two independent N—H⋯ N hydrogen bonds, but into chains of edge-fused R22 (8) and R44 (10) rings.