Preparation of trifluoromethyl and other perfluoroalkyl compounds with (perfluoroalkyl) trimethylsilanes

R Krishnamurti, DR Bellew…

Index: Krishnamurti, Ramesh; Bellew, Donald R.; Prakash, G. K. Surya Journal of Organic Chemistry, 1991 , vol. 56, # 3 p. 984 - 989

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Citation Number: 227

Abstract

The preparation of a variety of novel perfluoroalkyl-substituted compounds in high yields using easily prepared (perfluoroalky1) trimethylsilanes (la-c) is described.(Trifluoromethy1)- ,(pentafluoroethy1)-, and (hepta-fluoropropyl) trimethylsilane, la-c, respectively, react readily with carbonyl compounds, such as aldehydes and ketones, by a fluoride-initiated catalytic process. Fluoride-initiated addition of 1 to a carbonyl group generates an oxyanionic ...