Chinese Journal of Chromatography 2000-07-01

[Determination of alpha-naphthylacetic acid by high performance liquid chromatography].

Y P Li, H J Yang, C H Peng, X Y Zhang

Index: Se Pu 18(4) , 372-3, (2000)

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Abstract

A high performance liquid chromatographic method for the determination of alpha-naphthylacetic acid has been established on a Hypersil C18 column(4.6 mm i.d. x 250 mm, 5 microns), with the mobile phase of methanol-water-phosphoric acid(60:40:0.35, V/V), and UV detection at 272 nm. The linear correlation was observed within the range of 16 mg/L-1,000 mg/L(r = 0.9997). The RSD was 0.8%(n = 5). The method is simple and accurate.