Toxicology Letters 1983-05-01

Effect of chronic herbicide intoxication on in vivo activities of certain enzymes in the liver of freshwater fish Nemachelius denisonii (day).

S S Rashatwar, R Ilyas

Index: Toxicol. Lett. 16(3-4) , 249-52, (1983)

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Abstract

Effect of 120 days of continuous exposure of three sublethal concentrations (1/2, 1/4 and 1/8 fractions of 96 h LC50) of Basalin on alkaline phosphatase (Alk P), acid phosphatase (Acid P), lactic dehydrogenase (LDH), succinic dehydrogenase (SDH), glutamic oxaloacetic transaminase (GOT), and glutamic pyruvic transaminase (GPT) activities in the liver of Nemacheilus denisonii were studied. Alk P, Acid P, LDH, and GPT activities were significantly inhibited, but GOT activities were not significantly altered. More inhibition was observed with the higher concentration, but Acid P, LDH, and GPT activities were significantly inhibited in all three sublethal concentrations.