Archives Internationales de Pharmacodynamie et Therapie 1986-04-01

Combined effects of high doses of rolitetracycline and testosterone on the liver of mice.

H Götz, R Böcker, C J Estler

Index: Arch. Int. Pharmacodyn. Ther. 280(2) , 324-8, (1986)

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Abstract

The effects of rolitetracycline (50 micrograms/g i.v.) and testosterone proprionate (4 X 1 micrograms/g s.c.) singly and combined on liver weight, serum GPT, SDH and bromsulfophthalein clearance have been measured in young mice. Pretreatment with testosterone tended to enhance the effects of rolitetracycline on the serum enzymes but was otherwise not effective.