Bioorganic & Medicinal Chemistry Letters 2003-10-20

Fungicide chinomethionate as a new family of photoinducible DNA-cleaving agents.

Jianying Qi, Tianhu Li, Albert S C Chan

Index: Bioorg. Med. Chem. Lett. 13(20) , 3561-3, (2003)

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Abstract

It is demonstrated for the first time in this report that chinomethionate is capable of causing efficient DNA cleavage under mild irradiation conditions, a fungicide molecule that processes the simple group of 1,3-dithio-2-one as its reactive functionality.