Mercapturic Acids (N-AcetylcysteineS-Conjugates) as Endogenous Substrates for the Renal Organic Anion Transporter-1

JM Pombrio, A Giangreco, L Li, MF Wempe…

Index: Molecular Pharmacology, , vol. 60, # 5 p. 1091 - 1099

Full Text: HTML

Citation Number: 45

Abstract

... For each molecule, an Austin-model 1 (AM1) semiempirical calculation and an ab initio ... been known that mercapturic acids are excreted in urine, the molecular mechanisms have ... uptake of a variety of structurally unrelated extracellular organic molecules, including nonsteroidal ...