RSC Advances

A FRET-based rhodamine–benzimidazole conjugate as a Cu 2+-selective colorimetric and ratiometric fluorescence probe that functions as a cytoplasm marker

S Goswami, S Maity, AC Maity, AK Maity, AK Das…

Index: Goswami, Shyamaprosad; Maity, Sibaprasad; Maity, Annada C.; Maity, Anup Kumar; Das, Avijit Kumar; Saha, Partha RSC Advances, 2014 , vol. 4, # 12 p. 6300 - 6305

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Citation Number: 14

Abstract

On the basis of fluorescence resonance energy transfer (FRET) from benzimidazole to a rhodamine moiety, a rhodamine–benzimidazole conjugate (RBC) ratiometric fluorescent probe has been designed and synthesized. The RBC selectively binds to Cu2+, showing visually observable changes in absorption and emission behavior, and demonstrates an effective intracellular Cu2+ imaging ability, allowing it to function as a cytoplasm marker.