Chemical & Pharmaceutical Bulletin 2000-04-01

Cardenolide and oxypregnane glycosides from the root of Asclepias incarnata L.

T Warashina, T Noro

Index: Chem. Pharm. Bull. 48(4) , 516-24, (2000)

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Abstract

Twenty-nine new oxypregnane glycosides were obtained along with two known cardenolides, frugoside and gofruside, and three known 12-O-acylated pregnane glycosides from the roots of Asclepias incarnata L. (Asclepiadaceae). By detailed studies of the 1H- and 13C-NMR spectra, the structures were determined to be tri- to penta glycosides of isolineolon, 12-O-acetyllineolon, ikemagenin, 12-O-benzoylisolineolon, and two new 12-O-acylated pregnanes.