Abstract 1-Aryl-4, 4, 4-trifluoro-1, 3-butanediones 1 react with β-amino-β-arylacrylonitrile 2, readily available from acetonitrile with aryl nitriles in the presence of potassium t-butoxide, to afford the corresponding 2, 6-diaryl-3-cyano-4-(trifluoromethyl) pyridines 3 in moderate to excellent yields.