Journal of Organic Chemistry 2006-10-13

Molecular iodine-catalyzed facile procedure for N-Boc protection of amines.

Ravi Varala, Sreelatha Nuvula, Srinivas R Adapa

Index: J. Org. Chem. 71 , 8283, (2006)

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Abstract

An efficient and practical protocol for the protection of various structurally and electronically divergent aryl and aliphatic amines using (Boc)2O in the presence of a catalytic amount of molecular iodine (10 mol %) under solvent-free conditions at ambient temperature is presented.

Structure	Name/CAS No.	Molecular Formula	Articles
	N-Boc-piperazine CAS:57260-71-6	C₉H₁₈N₂O₂

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Molecular iodine-catalyzed facile procedure for N-Boc protection of amines.

Abstract

Related Compounds