Synthesis and inhibitory effects of pinosylvin derivatives on prostaglandin E 2 production in lipopolysaccharide-induced mouse macrophage cells

EJ Park, HY Min, YH Ahn, CM Bae, JH Pyee…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 23 p. 5895 - 5898

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Citation Number: 61

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... time that pinosylvin is also one of active natural stilbenoids exhibiting an appreciable inhibitory activity against the overproduction of the inflammatory mediator PGE 2 , and could serve as a new lead for further chemical optimization. ...