Tetrahedron Letters

A simple route to 9-fluorenylidenes by domino Suzuki/Heck coupling reactions

S Paul, T Gorai, A Koley, JK Ray

Index: Paul, Sunanda; Gorai, Tumpa; Koley, Arijit; Ray, Jayanta K. Tetrahedron Letters, 2011 , vol. 52, # 31 p. 4051 - 4055

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Citation Number: 28

Abstract

9-Fluorenylidene derivatives have attracted interest from synthetic organic chemists due to their notable biological and pharmaceutical importance and applications. They represent the core structural unit in several biologically active molecules. Many dermatological and photostable cosmetic compositions consist of lumefantrine, a 9-fluorenylidene derivative. 1 Paranylene is used in dispersible formulations of anti-inflammatory agents. 2 β-Phenyl-β-fluorenylidene- ...