Agents and actions. Supplements 1991-01-01

A new antiinflammatory agent (EGIS-5645) without gastrointestinal side-effect.

G Gigler, E Kiszelly, P Tömpe, G Kovács, K Gadó

Index: Agents Actions. Suppl. 32 , 39-43, (1991)

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Abstract

The compound EGIS-5645 is a potent antipyretic agent possessing analgesic and antiinflammatory properties. The drug is active in antiinflammatory models such as carrageenin oedema and adjuvant arthritis. EGIS-5645 shows practically no gastro-ulcerogenic effect. The molecule does not inhibit either prostaglandin biosynthesis or soybean lipoxygenase enzyme activity.