Natural Product Research 2003-08-01

Morierinin: a new cytotoxic cucurbitacin from the leaves of Morierina montana Vieill.

Marc Litaudon, Christianne Gaspard, Thierry Sévenet

Index: Nat. Prod. Res. 17(4) , 229-33, (2003)

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Abstract

An extract of the leaves of Morierina montana collected in New Caledonia was found to be cytotoxic for KB cells. A bioassay-guided fractionation procedure led to the isolation of a series of cucurbitacins of which one, morierinin (1), is new. The isolation and structure elucidation of 1 are described.