Aryl bromides with strongly electron-donating substituents generally do not undergo the triphenylphosphinepalladium acetate catalyzed vinylic substitution reaction in acceptable yields. Competing formation of tetraaryl-phosphonium salts from the aryl bromide and, in some cases, reduction of the aryl bromide to the arene occur. Significant improvements in yield are often obtained when tri-o-tolylphosphine is used in place of triphenylphosphine. ...
![2-Propenoic acid,3-[2-(acetyloxy)phenyl]-, methyl ester, (2E)- Structure](https://image.chemsrc.com/caspic/278/6286-83-5.png)
