Journal of the American Chemical Society

A Study of the Cyclization of a Series of ι, ι'-Dicarbethoxydialkylmethylamines through the Acetoacetic Ester Condensation

EA Prill, SM McElvain

Index: Prill, E. A.; McElvain, S. M. Journal of the American Chemical Society, 1933 , vol. 55, p. 1233 - 1241

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Citation Number: 31

Abstract

There are numerous examples in the literature of the application of an internal acetoacetic ester condensation (the Dieckmann reaction) to the synthesis of cyclic P-keto esters. Dieckmann'first used this reaction for the synthesis of five, six and seven membered alicyclic ring structures. In the heterocyclic field use has been made of this reaction in the preparation of both monocyclic and bicyclic systems containing nitrogen as the hetero atom.* In this ...