L O Minushkina, I K Iosava
Index: Kardiologiia 52(12) , 70-4, (2012)
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This review summarizes data on the effectiveness of lercanidipine. Lercanidipine is dihydropyridine calcium antagonist of the third generation, characterized by high vazoselective, long duration of action and good antihypertensive effect. It may be assigned to elderly patients with isolated hypertension and has several important organoprotective properties. Treatment with lercanidipine promotes nephroprotection, reduction of left ventricular hypertrophy, improvement of elastic properties of blood vessels and reduction of central pressure. Sympathetic activation in the application of lercanidipine is virtually absent, that ensures its good tolerability and high adherence of patients to treatment.
| Structure | Name/CAS No. | Molecular Formula | Articles |
|---|---|---|---|
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Lercanidipine hydrochloride
CAS:132866-11-6 |
C36H42ClN3O6 |
|
Differences in lercanidipine systemic exposure when administ...
2012-07-01 [Eur. J. Clin. Pharmacol. 68(7) , 1043-7, (2012)] |
|
Rationale for the use of a fixed-dose combination in the man...
2010-01-01 [Clin. Drug Investig. 30(12) , 843-54, (2010)] |
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Lercanidipine rescues hippocampus pyramidal neurons from mil...
2011-05-01 [Cell. Mol. Neurobiol. 31(4) , 561-7, (2011)] |
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Incidence and clinical course of lercanidipine-associated cl...
2010-09-01 [Clin. Nephrol. 74(3) , 217-22, (2010)] |
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Polymorphism of the methylenetetrahydrofolate reductase gene...
2012-06-01 [Gene 500(2) , 207-10, (2012)] |
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