Chemical Communications 2010-09-21

Complete determination of natural site-specific enantio-isotopomeric excesses in linoleic acid using natural abundance deuterium 2D NMR in polypeptide mesophases.

Zeinab Serhan, Laura Martel, Isabelle Billault, Philippe Lesot

Index: Chem. Commun. (Camb.) 46(35) , 6599-601, (2010)

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Abstract

NAD 2D NMR spectroscopy using chiral mesophases made of poly-gamma-benzyl-l-glutamate and pyridine allowed us to evaluate, for the first time, the natural site-specific enantio-isotopomeric excesses at each methylene group of linoleic acid, a central, essential PUFA precursor of all conjugated triene fatty acids.