Owing to our interest in the synthesis and bioactivity of 1, 2-dithiacyclohexa-3, 5-dienes [l, Pdithiins, eg. thiarubrine A (1) and thiarubrine B (2) 1, we are investigating the reactions of thiols with enediynes, polyenynes, and polyalkynes under various experimental Efficient syntheses of a wide variety of natural and unnatural 1, 2-dithiins2-11 and a study of structureactivity relationships (SAR) will help in gaining a better understanding of the ...
