(+)-cis-5, 7-Dihydroxy-2-methyl-8-[4-(3-hydroxy-1-methyl) piperidinyl]-4H-1-benzopyran-4- one was identified as the antiinflammatory cum immunomodulatory principle of the stem bark of Dysoxylum binectariferum. The sequence devised for its total synthesis was also used to synthesise its (-)-enantiomer and the racemate.