A series of N-aralkyltroponylpiperazine derivatives were synthesized and evaluated for dopaminergic activity in rats rendered hypokinetic by the bilateral injection of 6- hydroxydopamine (6-OHDA) into the anterolateral hypothalamus. Several members of the series were active, and a structure-activity relationship is presented. A few selected compounds were also evaluated with regard to their ability to induce contralateral ...
![2-{4-[2-(3,4-Dimethoxy-phenyl)-2-hydroxy-ethyl]-piperazin-1-yl}-cyclohepta-2,4,6-trienone Structure](https://image.chemsrc.com/caspic/169/80101-33-3.png)
