A number of 3-amino-2-oxazolidones have been prepared by the cyclization of 2-(2- hydroxyalkyl)-semicarbazides with hydrochloric acid, the condensation of P-hydrazino alcohols with some carbonic acid esters and chlorides and the catalytic or electrolytic reduction of 3-nitro-2-oxazolidones. These 3-amino-2-oxazolidone have been converted to chemotherapeutically active 5-nitro-2-acylfuran derivatives.
![2-Oxazolidinone,5-methyl-3-[[(5-nitro-2-furanyl)methylene]amino]- Structure](https://image.chemsrc.com/caspic/452/6281-26-1.png)
![3-[(E)-[(Z)-3-(5-nitrofuran-2-yl)prop-2-enylidene]amino]-1,3-oxazolidin-2-one Structure](https://image.chemsrc.com/caspic/049/3318-78-3.png)