Journal of Bacteriology 2009-09-01

Isoprenoids are essential for fruiting body formation in Myxococcus xanthus.

Wolfram Lorenzen, Michael W Ring, Gertrud Schwär, Helge B Bode

Index: J. Bacteriol. 191 , 5849-5853, (2009)

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Abstract

It was recently shown that Myxococcus xanthus harbors an alternative and reversible biosynthetic pathway to isovaleryl coenzyme A (CoA) branching from 3-hydroxy-3-methylglutaryl-CoA. Analyses of various mutants in these pathways for fatty acid profiles and fruiting body formation revealed for the first time the importance of isoprenoids for myxobacterial development.