2-(Alkylamino) nicotinic acid and analogs. Potent angiotensin II antagonists

M Winn, B De, TM Zydowsky…

Index: Journal of Medicinal Chemistry, , vol. 36, # 18 p. 2676 - 2688

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Citation Number: 27

Abstract

... On the basis of the success of the angiotensin-converting enzyme inhibitors as antihypertensive drugs, there has been intenae effort in the pharmaceutical industry to discover renin inhibitors and angiotensin I1 (A-11) antagonists as ... Journal of Medicinal Chemistry, 1993, Vol. ...