e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Synthesis of homochiral 5-and 8-substituted 2-[((2-(2, 6-dimethoxyphenoxy)-ethyl) amino) methyl]-1, 4-benzodioxanes and electrophoretic determination of their …
…, M Pallavicini, L Villa, D Pezzetta
Index: Valoti; Pallavicini; Villa; Pezzetta Journal of Organic Chemistry, 2001 , vol. 66, # 3 p. 1018 - 1025
Among the structures which have the capacity to interact with R1-adrenoceptors, benzodioxanes are one of the main classes. In particular, WB4101, which can be considered the lead compound of such a class, exhibits a nanomolar affinity toward R1- adrenoceptor, the S enantiomer possessing remarkably higher affinity than the R enantiomer. 1 As part of our ongoing program aimed at the study of chiral benzodioxane ...
