Semisynthesis of Flexible 5, 7??Dideoxypaclitaxel Derivatives from Taxine B

PH Beusker, H Veldhuis…

Index: European Journal of Organic Chemistry, , # 9 p. 1761 - 1768

Full Text: HTML

Citation Number: 3

Abstract

... European Journal of Organic Chemistry. ... The derivatives have been prepared from taxine (6), an alkaloid mixture isolated from the leaves of the European Yew, Taxus baccata ... 1 H, J 9−10 = 9.4 Hz, 9-H), 4.74 (d, 1 H, J 10−9 = 9.4 Hz, 10-H), 5.02 (d, 1 H, 2′-H), 5.60 (d, 1 H, J 2−3 ...