Abstract A convenient route is reported for the synthesis of seven new pyrimidine derivatives namely: 2-bromometh-yl-4, 6-dimethoxypyrimidine (3), 2-dibromomethyl-4, 6- dimethoxypyrimidine (4), 2-acetoxymethyl-4, 6-dimeth-oxypyrimidine (5), 2-hydroxymethyl-4,