New anilinophthalazines as potent and orally well absorbed inhibitors of the VEGF receptor tyrosine kinases useful as antagonists of tumor-driven angiogenesis

G Bold, KH Altmann, J Frei, M Lang…

Index: Journal of Medicinal Chemistry, , vol. 43, # 12 p. 2310 - 2323

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Citation Number: 257

Abstract

... Journal of Medicinal Chemistry. ... Oncology Research, and Process Research, NOVARTIS Pharma AG, CH-4002 Basel, Switzerland, and Institute of Molecular Medicine, Tumor Biology Center, D-79106 Freiburg, Germany. J. Med. Chem. ...