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e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521

Novel carbamate cholinesterase inhibitors that release biologically active amines following enzyme inhibition

JC Verheijen, KA Wiig, S Du, SL Connors…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 19, # 12 p. 3243 - 3246

Full Text: HTML

Citation Number: 11

Abstract

... Please enable JavaScript to use all the features on this page. Bioorganic & Medicinal Chemistry Letters. Volume 19, Issue 12, 15 June 2009, Pages 3243–3246. ... Towards the end of the 19th century, physostigmine found medicinal use in the treatment of glaucoma. ...

 Related Synthetic Route
3-((S)-1-(dimethylamino)ethyl)phenyl ((S)-1-phenylpropan-2-yl)carbamate hydrochloride Structure

1247027-68-4

3-((S)-1-(dimet...

~%

Carbon dioxide Structure

124-38-9

Carbon dioxide

D-AMPHETAMINE HYDROCHLORIDE Structure

51-64-9

D-AMPHETAMINE H...

3-[(1S)-1-(Dimethylamino)ethyl]phenol Structure

139306-10-8

3-[(1S)-1-(Dime...

N/A Structure

1247027-69-5

N/A

~%

Carbon dioxide Structure

124-38-9

Carbon dioxide

l-amphetamine Structure

156-34-3

l-amphetamine

3-[(1S)-1-(Dimethylamino)ethyl]phenol Structure

139306-10-8

3-[(1S)-1-(Dime...

N/A Structure

1247027-70-8

N/A

~%

Carbon dioxide Structure

124-38-9

Carbon dioxide

D-Methamphetamine Structure

537-46-2

D-Methamphetamine

3-[(1S)-1-(Dimethylamino)ethyl]phenol Structure

139306-10-8

3-[(1S)-1-(Dime...

3-((S)-1-(dimethylamino)ethyl)phenyl methyl((R)-1-phenylpropan-2-yl)carbamate hydrochloride Structure

1247027-71-9

3-((S)-1-(dimet...

~%

Carbon dioxide Structure

124-38-9

Carbon dioxide

(-)-2-[methylamino]-1-phenylpropane Structure

33817-09-3

(-)-2-[methylam...

3-[(1S)-1-(Dimethylamino)ethyl]phenol Structure

139306-10-8

3-[(1S)-1-(Dime...

Rivastigmine Structure

123441-03-2

Rivastigmine

~%

Ethylmethylamine Structure

624-78-2

Ethylmethylamine

Carbon dioxide Structure

124-38-9

Carbon dioxide

3-[(1S)-1-(Dimethylamino)ethyl]phenol Structure

139306-10-8

3-[(1S)-1-(Dime...

N/A Structure

1247027-70-8

N/A

~%

Carbon dioxide Structure

124-38-9

Carbon dioxide

D-Methamphetamine Structure

537-46-2

D-Methamphetamine

3-[(1S)-1-(Dimethylamino)ethyl]phenol Structure

139306-10-8

3-[(1S)-1-(Dime...

Rivastigmine Structure

123441-03-2

Rivastigmine

~%

Ethylmethylamine Structure

624-78-2

Ethylmethylamine

Carbon dioxide Structure

124-38-9

Carbon dioxide

3-[(1S)-1-(Dimethylamino)ethyl]phenol Structure

139306-10-8

3-[(1S)-1-(Dime...

3-((S)-1-(dimethylamino)ethyl)phenyl methyl((R)-1-phenylpropan-2-yl)carbamate hydrochloride Structure

1247027-71-9

3-((S)-1-(dimet...

~%

Carbon dioxide Structure

124-38-9

Carbon dioxide

(-)-2-[methylamino]-1-phenylpropane Structure

33817-09-3

(-)-2-[methylam...

3-[(1S)-1-(Dimethylamino)ethyl]phenol Structure

139306-10-8

3-[(1S)-1-(Dime...

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Detail Synthetic Route


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