Tetrahedron

Salt/ligand-activated low-valent titanium formulations: the 'salt effect'on diastereoselective carbon–carbon bond forming SET reactions

SM Rele, SK Nayak, S Chattopadhyay

Index: Rele, Shyam M.; Nayak, Sandip K.; Chattopadhyay, Subrata Tetrahedron, 2008 , vol. 64, # 30-31 p. 7225 - 7233

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Citation Number: 12

Abstract

A comprehensive study on the influence of exogenously added electropositive metal salts as promoters/secondary activators on preformed LVT species has resulted in the construction of highly efficient low-valent titanium (LVT) reagents. These salt-activated LVT reagents while exhibiting enhanced chemoselectivity and diastereoselectivity accelerated the reductive olefination rates of aromatic and aliphatic carbonyls under ambient temperature ...