Synthesis of Functionalized Nitrogen Heterocycles by Radical Decarboxylation of β??and γ??Amino Acids

…, JR Murguía, A Rodriguez??Afonso

Index: Boto, Alicia; Hernandez, Rosendo; De Leon, Yolanda; Murguia, Jose R.; Rodriguez-Afonso, Abigail European Journal of Organic Chemistry, 2005 , # 4 p. 673 - 682

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Citation Number: 12

Abstract

Abstract Iodinated or oxygenated nitrogen heterocycles are obtained by radical decarboxylation of β-and γ-amino acids. This mild, versatile reaction is applied to the synthesis of bioactive products, such as 4-arylpiperidines, hydroxylated piperidines, and new antifungal agents.