Organic letters

Profiling of glycosidase activities using coumarin-conjugated glycoside cocktails

S Park, I Shin

Index: Park, Sungjin; Shin, Injae Organic Letters, 2007 , vol. 9, # 4 p. 619 - 622

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Citation Number: 16

Abstract

Glycosidases are a large subgroup of carbohydrate-processing enzymes that hydrolytically cleave the glycosidic bond. Glycans formed by the action of glycosidases are involved in various biological processes. Genetic abnormalities in glycosidases are associated with inherited diseases. Thus, characterization of the catalytic activities of glycosidases is of great importance. Herein, we describe a simple and rapid approach for determining glycosidase ...