Synthesis and Antiviral Activity of New Bisacridinylhydrazides of Aryloxyacetic Acids

SA Lyakhov, EA Lyakhova, NN Panchenko…

Index: Lyakhov; Lyakhova; Panchenko; Litvinova; Andronati Pharmaceutical Chemistry Journal, 2001 , vol. 35, # 12 p. 653 - 656

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Abstract

The class of aminoacridine derivatives contains compounds possessing antitumor [1], antimicrobial [2], and antiviral [3] properties. As for acridinylhydrazine derivatives, it was only established that some aryloxy acid acridinylhydrazides (I) exhibited fungicidal and schistosomiacidal activity [4–8]. Previously [9], we reported that biodegradable bisacridines (II, where X is a fragment containing amide or ester bonds) may possess significant ...