Synthesis and structure-activity relationships of 1-acyl-4-((2-methyl-3-pyridyl) cyanomethyl) piperazines as PAF antagonists

E Carceller, M Merlos, M Giral, C Almansa…

Index: Journal of Medicinal Chemistry, , vol. 36, # 20 p. 2984 - 2997

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Citation Number: 39

Abstract

... Assignment of the cis and trans stereochemistry was based on their proton NMR spectra through correlation of the observed chemical shifts for the ethylenic proton and the values calculated by addition of tabulated substituents ... Journal of Medicinal Chemistry, 1993, Vol. ...