Organic Letters 2009-04-02

Microcapsules with three orthogonal reactive sites.

Brian P Mason, Steven M Hira, Geoffrey F Strouse, D Tyler McQuade

Index: Org. Lett. 11(7) , 1479-82, (2009)

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Abstract

Polymeric microcapsules containing reactive sites on the shell surface and two orthogonally reactive polymers encapsulated within the interior are selectively labeled. The capsules provide three spatially separate and differentially reactive sites. Confocal fluorescence microscopy is used to characterize the distribution of labels. Polymers encapsulated are distributed homogeneously within the core and do not interact with the shell even when oppositely charged.