International Journal of Dermatology 2010-05-01

Positive concomitant test reactions to allergens in the standard patch test series.

Lilla Landeck, Ernesto González, Lynn Baden, Konrad Neumann, Peter Schalock

Index: Int. J. Dermatol. 49(5) , 517-9, (2010)

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Abstract

Patch testing is performed to evaluate suspected allergic contact dermatitis. Common wisdom suggests that various allergens cross-react but only a few larger studies have published confirmations of this. The purpose of our study was to identify significant correlations between positive test reactions in a screening series.A total of 1235 patients undergoing patch testing to the Hermal standard series at the Massachusetts General Hospital, Contact Dermatitis Clinic between 1990 and 2006 were investigated.Two or more positive reactions were seen in 411 patients (33.3%). Sensitizations to eight pairs of allergens were found to have significant correlation (P