Tetrahedron Letters

Amberlyst-15: a mild, efficient and reusable heterogeneous catalyst for N-tert-butoxycarbonylation of amines

KS Kumar, J Iqbal, M Pal

Index: Kumar, K. Shiva; Iqbal, Javed; Pal, Manojit Tetrahedron Letters, 2009 , vol. 50, # 46 p. 6244 - 6246

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Citation Number: 32

Abstract

A mild and versatile method has been developed for the chemoselective N-tert- butoxycarbonylation of amines in the presence of Amberlyst-15 under solvent-free condition. The method is general for the preparation of N-Boc derivatives of aliphatic (acyclic and cyclic) and aromatic amines.