e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Advanced Synthesis & Catalysis
A Modular Furanoside Thioether??Phosphite/Phosphinite/Phosphine Ligand Library for Asymmetric Iridium??Catalyzed Hydrogenation of Minimally Functionalized …
Abstract A highly modular furanoside thioether-phosphite/phosphinite/phosphine ligand library has been synthesized for the iridium-catalyzed asymmetric hydrogenation of minimally functionalized olefins. These ligands can be prepared efficiently from easily accessible D-(+)-xylose. We found that their effectiveness at transferring the chiral information in the product can be tuned by correctly choosing the ligand components. ...
