Chemical Communications 2012-02-14

An efficient palladium-benzimidazolyl phosphine complex for the Suzuki-Miyaura coupling of aryl mesylates: facile ligand synthesis and metal complex characterization.

Kin Ho Chung, Chau Ming So, Shun Man Wong, Chi Him Luk, Zhongyuan Zhou, Chak Po Lau, Fuk Yee Kwong

Index: Chem. Commun. (Camb.) 48 , 1967, (2012)

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Abstract

A new class of easily accessible hemilabile benzimidazolyl phosphine ligands has been developed. The ligand skeleton is prepared from commercially available and inexpensive o-phenylenediamine and 2-bromobenzoic acid. With catalyst loading down to 0.5 mol% palladium, excellent catalytic activity towards the Suzuki-Miyaura coupling of aryl mesylates is still observed. This represents the lowest catalyst loading achieved so far for this reaction in general. X-Ray crystallography shows that new ligand L2 is coordinated with Pd in a κ(2)-P,N fashion.This journal is © The Royal Society of Chemistry 2012