Microwave??accelerated synthesis of benzyl 3, 5??dimethyl??pyrrole??2??carboxylate

J Regourd, IM Comeau, CS Beshara…

Index: Regourd, Jasmine; Comeau, Ian M.; Beshara, Cory S.; Thompson, Alison Journal of Heterocyclic Chemistry, 2006 , vol. 43, # 6 p. 1709 - 1714

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Citation Number: 9

Abstract

The chemistry of substituted pyrroles is a challenging field that often relies on traditional reactions using harsh conditions, eg. very high temperatures for extended periods of time, or highly acidic/caustic conditions. Many reactions for the synthesis (or functional group interconversion) of pyrroles were first introduced several decades ago, with little refinement having been reported since then. Benzyl 3, 5-dimethyl-pyrrole-2-carboxylate 1 is a very ...